77 citations
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April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
76 citations
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July 2011 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.
72 citations
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June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
67 citations
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December 2011 in “Stem Cells and Development” NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.
66 citations
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May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
65 citations
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July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
64 citations
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August 2007 in “Artificial Organs” PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
61 citations
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June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
60 citations
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November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
58 citations
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September 2019 in “EMBO Molecular Medicine” CDK4/6 inhibitors can protect hair cells from chemotherapy damage.
57 citations
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January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
55 citations
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April 2015 in “BMC medicine” Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
54 citations
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December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
53 citations
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April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
50 citations
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August 2021 in “Stem Cell Research & Therapy” Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
48 citations
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March 2020 in “Stem Cell Research & Therapy” Using a collagen sponge scaffold helps stem cells become more like skin cells.
47 citations
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October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
45 citations
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April 2013 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
44 citations
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
39 citations
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April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
39 citations
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September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
37 citations
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February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
36 citations
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February 2017 in “BMC Complementary and Alternative Medicine” Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.
36 citations
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May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
33 citations
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September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
32 citations
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May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
31 citations
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June 2022 in “Stem Cell Research & Therapy” CD146 + mesenchymal stem cells are more effective for treating premature ovarian failure.
31 citations
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April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
28 citations
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February 2021 in “Stem Cell Research & Therapy” Placental cell medium boosts blood vessel growth in lab tests.