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Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.

The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.

A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.

SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.

Phospholipase Cδ1 is crucial for normal skin and hair development.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Keratin 17 gene mutations cause both steatocystoma multiplex and pachyonychia congenita type 2.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Cow milk sugars increase fat production and inflammation in skin oil cells.