175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
11 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
242 citations
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February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
January 2026 in “Journal of Biomedical Research” Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.
1 citations
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October 2013 Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
6 citations
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December 2021 in “PLoS Genetics” Polycomb Repressive Complex 2 is not needed for hair regeneration.
December 2025 in “EMBO Reports” Cells communicate with neighbors to coordinate their development.
82 citations
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July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
April 2020 in “Journal of animal research” Canine hair follicles have stem cells in the bulge region.
April 2026 in “Research Square” COVID-19 can harm male fertility by reducing sperm stem cells and damaging testicular function.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
18 citations
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September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
57 citations
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January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
23 citations
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May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
2 citations
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April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
December 2024 in “Stem Cell Research & Therapy” ZO-1 helps hair follicle stem cells renew better by changing their structure.
6 citations
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November 2023 in “Stem Cell Reports” Stem cells in the cornea show unexpected flexibility and have important implications for medicine.
5 citations
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August 2020 in “Stem Cell Research & Therapy” Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
September 2025 in “Stem Cell Research & Therapy” TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
949 citations
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January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
338 citations
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April 2001 in “Current Biology” c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
164 citations
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
54 citations
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January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
December 2025 in “Cell Communication and Signaling” Minoxidil may help treat myelodysplastic syndrome without harming normal blood cell production.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
28 citations
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April 2024 in “Immunity” CD80 on skin stem cells helps expand Treg cells to aid wound healing.
July 2025 in “Interdisciplinary materials” A microneedle patch with curcumin and stem cell components effectively treats hypertrophic scars and promotes healing.