61 citations
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July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
23 citations
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June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
14 citations
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November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
1 citations
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January 2019 in “Journal of Embryology & Stem Cell Research” MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
294 citations
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
105 citations
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October 2018 in “Nature” A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
84 citations
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December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
55 citations
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March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
41 citations
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April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
19 citations
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September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
13 citations
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September 2017 in “Cytometry Part A” Horse hair follicles could be a new source of stem cells for healing horses.
1 citations
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November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
December 2022 in “Nature Communications” Bead-jet printing of stem cells improves muscle and hair regeneration.
150 citations
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October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
101 citations
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March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
95 citations
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October 2020 in “Cell & Bioscience” Mesenchymal stem cell therapy shows promise for liver disease but faces challenges in standardization and approval.
42 citations
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July 2010 in “European Journal of Cell Biology” Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.
10 citations
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May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
7 citations
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September 2017 in “Scientific Reports” Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
4 citations
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April 2019 in “Cell Stem Cell” Certain immune cells in the skin can stop hair from growing.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
23 citations
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November 2011 in “Journal of the European Academy of Dermatology and Venereology” Hair loss is a rare but recognized symptom of pemphigus vulgaris, with patients usually regrowing hair after treatment.
4 citations
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June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
9 citations
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January 2021 in “International Journal of Medical Sciences” Sox10 is important for hair follicle development and hair growth cycles.
June 2025 in “Cell Metabolism” Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.