8 citations
,
April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
8 citations
,
September 2002 in “Genes to Cells” Killing specific cells in hair follicles can lead to hair growth problems in mice.
7 citations
,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
6 citations
,
February 2010 in “Biotechnology and bioprocess engineering” Using umbilical cord stem cells can help create hair-growing tissues more affordably.
6 citations
,
November 2023 in “JCI Insight” Exogenous stem cells can effectively integrate into hair follicles, promoting hair growth.
March 2025 in “Regenerative Therapy” Spirulina maxima extract may help hair growth by boosting cell activity.
January 2019 in “Publisher” Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
July 2018 in “Elsevier eBooks” New hair loss treatments show promise, but more research is needed to confirm their effectiveness.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
March 2015 in “Zagazig University Medical Journal” Damage to hair follicle stem cells may cause permanent hair loss and scarring in PCA.
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
September 2015 in “International Society of Hair Restoration Surgery” Hair follicle stem cells could lead to new hair loss treatments.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
57 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
24 citations
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January 2019 in “Theranostics” Loss of Pten in certain hair follicle stem cells increases skin cancer risk.
14 citations
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February 2008 in “Stem Cells and Development” Seven genes are highly expressed in both germ-line and hematopoietic stem cells.
12 citations
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September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.
5 citations
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May 2024 in “Journal of Cosmetic Dermatology” Engineered nanovesicles from hair follicle stem cells can effectively treat UVB-induced skin aging.
4 citations
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October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” G2 stem cells control calcium signaling for skin regeneration.
4 citations
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January 2016 in “Methods in molecular biology” Hair follicle stem cells can become nerve cells using specific treatments.
2 citations
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September 2020 in “International Journal of Molecular Sciences” Removing certain hair follicle stem cells worsens skin reactions to allergens.
1 citations
,
July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
April 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
January 2018 in “eScholarship (California Digital Library)” Hair follicle stem cells may cause squamous cell carcinoma due to a metabolic shift towards glycolysis.
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.