May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
16 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” Wound healing can potentially regrow hair and aid in hair loss treatments.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
Wound-induced hair follicle creation is a complex process in adult mammals that involves various cells and immune responses, and understanding it better could help improve skin healing strategies.
150 citations
,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
67 citations
,
December 2011 in “Stem Cells and Development” NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
34 citations
,
August 2016 in “Scientific Reports” Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
24 citations
,
July 2015 in “Molecular Medicine Reports” Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.
7 citations
,
February 2018 in “Journal of Investigative Dermatology” Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
142 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
79 citations
,
November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
27 citations
,
June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
January 2024 in “Wiadomości Lekarskie” Ancient immune and signaling pathways still regulate blood cell development.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
June 2026 in “Journal of Cosmetic Dermatology” CGF-PF may improve hair loss treatment by targeting hair follicle stem cells more effectively.
January 2025 in “International Journal of Biological Macromolecules” Decorin helps hair growth by influencing specific cell signals.
5 citations
,
May 2020 in “Wiley Interdisciplinary Reviews Developmental Biology” Bone growth is controlled by both internal and external signals, involving stem cells and tissue interactions.
7 citations
,
April 2013 in “Journal of Cellular Biochemistry” CD61 is important for mouse tooth cell growth and works through Lgr5.
3 citations
,
January 2025 in “Biomaterials Science” Blue light-enhanced nanovesicles from stem cells improve skin and hair cell function, offering a safer treatment for skin and hair disorders.
1 citations
,
October 2025 in “PLoS ONE” LncRNA RP11-818O24.3 may help treat hair loss by boosting hair follicle stem cell growth and differentiation.
87 citations
,
August 2017 in “Differentiation” Stromal cells significantly influence Wnt signaling in the intestine, affecting cell growth and health.
7 citations
,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
December 2025 in “Cell Communication and Signaling” Minoxidil may help treat myelodysplastic syndrome without harming normal blood cell production.
35 citations
,
July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
April 2019 in “Institutional Repositories DataBase (IRDB)” Patient-derived stem cell melanocytes could be a promising treatment for vitiligo.
January 2009 in “Bradford Scholars (University of Bradford)” BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.
270 citations
,
March 2012 in “Dermatologic Surgery” Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
2 citations
,
August 2008 in “Oncotarget” Apoptosis in hair follicles spreads through cell death signals, with stem cells slowing the process.
6 citations
,
June 2021 in “The Journal of Experimental Medicine” Understanding signaling in blood cells is complex and still limited.