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RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development

research RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development

5 citations , July 2022 in “Orphanet journal of rare diseases”

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome

1 citations , May 2022 in “International journal of molecular sciences”

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

research Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis

December 2025 in “Cell Communication and Signaling”

Minoxidil may help treat myelodysplastic syndrome without harming normal blood cell production.

research CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

28 citations , April 2024 in “Immunity”

CD80 on skin stem cells helps expand Treg cells to aid wound healing.

research ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway

18 citations , February 2022 in “Cell Death Discovery”

ECM1-modified stem cells can effectively treat liver cirrhosis.

research Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research

17 citations , January 2023 in “Frontiers in Cell and Developmental Biology”

iPSCs are promising for studying and treating COVID-19.

research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt^WT mice

8 citations , September 2013 in “Molecular carcinogenesis”

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing

5 citations , April 2022 in “Frontiers in Medicine”

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

research Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways

9 citations , February 2025 in “Journal of Nanobiotechnology”

Biomimetic nanovesicles can speed up diabetic wound healing by regulating immune cell behavior and metabolism.

research Deciphering Early-Stage Molecular Mechanisms of Negative Pressure Wound Therapy in a Murine Model

2 citations , February 2024 in “International Journal of Molecular Sciences”

Negative Pressure Wound Therapy speeds up wound healing by reducing inflammation and promoting skin cell growth.

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