253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
124 citations
,
February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
91 citations
,
December 2010 in “Stem Cells” Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
76 citations
,
July 2019 in “Cellular and Molecular Life Sciences” Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
63 citations
,
April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
23 citations
,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
15 citations
,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
11 citations
,
October 2018 in “The Journal of Dermatology” Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
10 citations
,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.
9 citations
,
January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
7 citations
,
January 2016 in “Methods in molecular biology” Mouse hair follicle stem cells were successfully isolated and used to regenerate hair follicles with two different methods.
6 citations
,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
5 citations
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January 2005 in “Cytotherapy” The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
9 citations
,
June 2020 in “Cell stem cell” Skinny fat cells help wounds heal faster by releasing fatty acids.
84 citations
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December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
1 citations
,
January 2019 in “Journal of Embryology & Stem Cell Research” MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
138 citations
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June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
8 citations
,
May 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.
4 citations
,
August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
363 citations
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March 2017 in “Nature Communications” Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
232 citations
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
211 citations
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November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.