January 2025 in “Antioxidants” SHED-CM can reduce hair graying and protect against damage from X-rays.
December 2022 in “Scientific Reports” Stem cells from whiskers can be transplanted to stimulate hair growth.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
19 citations
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January 2021 in “Experimental dermatology” Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.
7 citations
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October 2011 in “International Surgery” In 2011, hair restoration was a specialized field in plastic surgery, using techniques like "Ultrarefined follicular unit hair transplantation" to minimize scarring and promote hair growth, with future treatments like stem cell therapy and hair cloning still being tested.
October 2022 in “Frontiers in Cell and Developmental Biology” Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
207 citations
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July 2006 in “Development” MTS24 marks a new type of skin cell that helps hair growth and repair.
163 citations
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April 2019 in “Nature Communications” Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
132 citations
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
66 citations
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March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
57 citations
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February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
48 citations
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
31 citations
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
31 citations
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October 2019 in “Genes & Diseases” Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
25 citations
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May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
16 citations
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December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
14 citations
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November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
5 citations
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May 2024 in “BMC Biotechnology” Using Matrigel with stem cells improves tissue healing.
4 citations
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January 2016 in “Methods in molecular biology” Hair follicle stem cells can become nerve cells using specific treatments.
3 citations
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November 2011 in “Small GTPases” Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
1 citations
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November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
479 citations
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January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
22 citations
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April 2023 in “The Journal of Cell Biology” Calcium signaling in skin cells is crucial for communication and regeneration.