50 citations
,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
July 2025 in “Reproductive Biology and Endocrinology” Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
36 citations
,
October 2009 in “Journal of biological chemistry/The Journal of biological chemistry” Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
146 citations
,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
17 citations
,
February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
12 citations
,
March 2004 in “Der Urologe” There is no strong evidence that chemopreventive agents effectively prevent prostate cancer.
13 citations
,
May 2007 in “Journal of Endocrinology” Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
December 2024 in “Research Journal of Pharmacy and Technology” Androgenic alopecia is mainly caused by DHT, and new treatments focus on hair regeneration and aging factors.
269 citations
,
May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
36 citations
,
October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
44 citations
,
March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
93 citations
,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
1 citations
,
February 2014 in “Archiv Der Pharmazie” Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
November 2023 in “Research Square (Research Square)” Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
57 citations
,
January 1995 in “The American journal of medicine” Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
57 citations
,
May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
49 citations
,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
26 citations
,
May 2013 in “Marine Drugs” Ishige sinicola, a type of seaweed, may help hair grow by blocking a hair loss-related enzyme and boosting important cell growth.
19 citations
,
January 2016 in “Biological & Pharmaceutical Bulletin” Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.
11 citations
,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
6 citations
,
January 2016 in “Evidence-based complementary and alternative medicine” Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.
2 citations
,
April 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
32 citations
,
May 2010 in “Pharmacopsychiatry” Finasteride reduces new brain cells in male mice, possibly causing depression.
5 citations
,
September 2009 in “Journal of Complementary and Integrative Medicine” Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
May 2024 in “Brazilian Journal of Hair Health” Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
112 citations
,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
January 2025 in “International Journal of Pharmacognosy and Clinical Research” The herbal scalp serum may help hair growth by reducing DHT levels.
75 citations
,
October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.