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Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Certain drugs that block specific enzymes can help treat prostate diseases.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

DHT affects testicular development and regulates spermatogenesis in some fish.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Dutasteride helps reduce heavy drinking, especially for those who drink to cope.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

New tests detect finasteride and dutasteride in urine quickly and easily.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Finasteride affects prostate weights and pituitary activity differently with age.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Certain Dibenzo derivatives may help treat prostate cancer.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

New compounds were made that effectively block a specific enzyme related to androgen conditions.