January 2020 in “Química Nova” The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.
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July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
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January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
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November 2006 in “International Journal of Cancer” A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.
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August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
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February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
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January 2016 in “Biological & Pharmaceutical Bulletin” Bee venom helps hair grow and may work better than some common treatments.
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October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
Compounds in fluted pumpkin and African yam bean seed oils may help manage benign prostate hyperplasia.
June 2023 in “International journal of pharmaceutical quality assurance” Eclipta alba extract could be a promising natural treatment for hair loss.
The models can help find better inhibitors for conditions like baldness and prostate disorders.
January 2024 in “Institutional Repositories DataBase (IRDB)” The method accurately measures steroid hormones in hair to study hormone dynamics related to hair loss.
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
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May 2018 in “International journal of risk & safety in medicine” Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.
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May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
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March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
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December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
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June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
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January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
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January 1982 in “Endocrinologia Japonica” Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.
May 2026 in “Frontiers in Pharmacology” Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.
July 2024 in “Biological and Pharmaceutical Bulletin” Licorice extract helps hair growth and may treat hair loss.
January 2022 in “Asian journal of Current Research in Clinical Cancer” Some dibenzo compounds might help treat cancer with fewer side effects.
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December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
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January 1991 in “Reproductive Toxicology” Finasteride temporarily lowers male rat fertility without affecting libido.
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
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August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
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January 2025 in “Frontiers in Pharmacology” Purple corn extract may help reduce prostate enlargement and inflammation.
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
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April 2017 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.