research Gender aspects in skin diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
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research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.
research Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase
Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review
Quercetin may help with PCOS symptoms, but more research is needed.
research Hirsutism: Diagnosis and management
The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
research Role of insulin resistance and diet in acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Effect of non-steroidal anti-inflammatory drugs on post-surgical complications against the backdrop of the opioid crisis
NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Role of Arachidonic Acid in Promoting Hair Growth
Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.
research Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review
Some plants with flavonoids may help treat hair loss and promote hair growth.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Management of Androgenetic Alopecia
Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
research Alopecia: unapproved treatments or indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Getting under the skin of hair aging: the impact of the hair follicle environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Dermatological problems of the puberty
Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
research Relating neurosteroid modulation of inhibitory neurotransmission to behaviour
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Dermatologic Problems of Older Women
Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
research PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields
Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
research The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia
Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
research The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific
Dutasteride and finasteride affect different cell types differently.