41 citations
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March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
41 citations
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April 2006 in “Hormone and metabolic research” Steroid-binding globulins have important roles beyond just transporting steroids.
39 citations
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April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
39 citations
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March 1976 in “British Journal of Dermatology” Intralesional steroid therapy is useful for treating various skin conditions.
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May 1982 in “PubMed” Intralesional steroid injections can effectively treat calcinosis and ulcers in scleroderma.
38 citations
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September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
37 citations
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
35 citations
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March 2013 in “American Journal of Medical Genetics Part B Neuropsychiatric Genetics” SRD5A2 gene variations affect PTSD symptoms differently in males and females.
35 citations
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September 1972 in “Journal of Biological Chemistry” Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.
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April 2014 in “Psychopharmacology” Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.