47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
47 citations
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November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
41 citations
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August 1988 in “Journal of The American Academy of Dermatology” A woman with subacute cutaneous lupus erythematosus had widespread skin symptoms triggered by medication and sunlight, which improved with specific treatments.
37 citations
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April 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
36 citations
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June 2017 in “Journal of Cutaneous Medicine and Surgery” The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.
33 citations
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June 2012 in “Journal of Crohn's and colitis” Alopecia Areata might be linked to Crohn's disease.
30 citations
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May 2014 in “American Journal of Clinical Dermatology” The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.
29 citations
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August 2008 in “Current Opinion in Pediatrics” Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
27 citations
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January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
26 citations
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March 2014 in “Journal of cutaneous medicine and surgery” Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.
26 citations
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January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
25 citations
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December 2022 in “Indonesian Journal of Science and Technology” Peanut stem extract has strong antioxidants and moderate cancer-fighting potential.
25 citations
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June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
23 citations
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January 2010 in “Journal of The American Academy of Dermatology” Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
20 citations
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January 2012 in “International journal of trichology” Steroids are the best treatment for Alopecia Areata with few side effects.
20 citations
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July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
18 citations
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January 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
18 citations
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December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
14 citations
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November 2008 in “Expert opinion on drug metabolism & toxicology” Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
13 citations
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June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
11 citations
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October 2018 in “Pediatric dermatology” Leflunomide and anthralin may effectively treat severe alopecia areata.
11 citations
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September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
11 citations
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August 2012 in “Canadian journal of ophthalmology” Eyelash alopecia areata often goes undiagnosed and can lead to complete eyelash regrowth, especially in younger patients.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
10 citations
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October 2010 in “Hepatology” Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
10 citations
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January 2010 in “Acta dermato-venereologica” Light therapy can effectively treat vitiligo and hair loss caused by a specific medication.
9 citations
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July 2021 in “Essays in Biochemistry” Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
9 citations
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February 2020 in “International Journal of Endocrinology” Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
9 citations
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August 2018 in “JAAD Case Reports” Tofacitinib can temporarily improve hair growth in alopecia universalis, but its effectiveness may decrease over time.
9 citations
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April 1986 in “Postgraduate Medicine” Hair loss has many causes and treatments, and losing some hair daily is normal; proper diagnosis is key, and minoxidil can help treat it.