12 citations
,
June 2005 in “Journal of the European Academy of Dermatology and Venereology” A man with HIV developed skin and hair issues after starting HIV treatment, which improved with topical treatment.
11 citations
,
November 2019 in “Clinical Case Reports” A Brazilian teenager with severe hair loss had total hair regrowth with no side effects after using tofacitinib.
11 citations
,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
January 2007 in “Journal of The American Academy of Dermatology” Propylthiouracil, a thyroid medication, can cause skin blood clots and immune-related blood vessel inflammation.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
January 1998 in “Current Therapeutics” Different causes of hair loss require specific treatments, and most men and women will experience some form of hair thinning as they age.
1 citations
,
October 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.
January 2014 in “edoc (University of Basel)” Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
29 citations
,
April 2020 in “Biomolecules” Brassinosteroids may be useful in treating cancer, infections, and other diseases.
14 citations
,
January 2020 in “Dermatology Online Journal” Some dietary supplements, like vitamins B6/B12, iodine, whey protein, and muscle-building products, can cause or worsen acne.
May 2018 in “KU ScholarWorks (The University of Kansas)” Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
31 citations
,
November 2014 in “Investigative Ophthalmology & Visual Science” A natural steroid in the body may protect against eye damage in glaucoma.
11 citations
,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
8 citations
,
October 2002 in “Journal Of Clinical Periodontology” Levamisole and finasteride can reduce DHT production, potentially preventing phenytoin-induced gum overgrowth.
22 citations
,
April 2004 in “Journal of Neurochemistry” Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.
October 2025 in “Journal of the Endocrine Society” Methimazole can cause severe low platelet count in Graves' disease patients, so monitoring and alternative treatments are important.
April 2008 in “Annals of General Psychiatry” Social isolation changes brain receptors and makes ethanol more impactful.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Various skin conditions can be treated effectively with different methods, such as discontinuing certain drugs, using specific vaccines, applying creams, and changing lifestyle habits like smoking and drinking.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, but it improves after stopping the drug. The glycoprotein D vaccine works against genital herpes in some women, and the HPV-16 vaccine reduces HPV-16 infection and related diseases. More frequent light therapy clears psoriasis faster. A cream called imiquimod effectively treats a type of skin cancer. Iron supplements don't necessarily help with chronic hair loss in women.
34 citations
,
March 2015 in “Clinical and Experimental Dermatology” People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.
27 citations
,
January 2017 in “Neuropsychopharmacology” The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
5 citations
,
January 2016 in “International Journal of Trichology” Erlotinib can cause hair loss and texture changes.
31 citations
,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
21 citations
,
January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
45 citations
,
September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D3 and its receptor help protect skin from UVB-related cancer.
18 citations
,
April 2010 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.
March 2026 in “The Journal of Steroid Biochemistry and Molecular Biology” Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.
Oral contraceptives may cause significant hair loss in women.
269 citations
,
May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
23 citations
,
July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.