46 citations
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March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
46 citations
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May 2011 in “Movement Disorders” Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
46 citations
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January 2007 in “The European Journal of Contraception & Reproductive Health Care” Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
46 citations
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August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
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August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
45 citations
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April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
45 citations
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March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
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July 2002 in “The Neurologist” A comprehensive approach to educating patients and managing side effects is crucial for improving adherence to multiple sclerosis treatments and patient quality of life.
44 citations
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January 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
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March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
42 citations
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September 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.
42 citations
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July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
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January 2006 in “Obstetrical & Gynecological Survey” The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
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January 2020 in “Journal of Ovarian Research” Quercetin may help with PCOS symptoms, but more research is needed.
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December 2019 in “Stem Cell Reviews and Reports” Tooth regeneration could become possible by controlling how and when bioactive factors are released.
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September 2014 in “JAMA Facial Plastic Surgery” Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.
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April 2010 in “Gender Medicine” The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
41 citations
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December 2008 in “Journal of the American Academy of Dermatology” Oral valganciclovir improved a patient's skin condition caused by immunosuppression.
40 citations
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August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
40 citations
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May 2014 in “PLoS ONE” Chronic stress can reduce skin pigmentation.
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October 2012 in “British Journal of Dermatology” Minoxidil helps regrow hair in female pattern hair loss, but more research needed for other treatments.
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April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
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April 1999 in “Drugs” Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
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April 2018 in “Hormones” No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
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August 2016 in “Journal of Dermatological Treatment” Stem cell therapy may help treat tough hair loss cases.
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May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
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May 2011 in “Movement Disorders” Finasteride may help reduce symptoms in male Tourette syndrome patients.