20 citations
,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
April 2012 in “Journal of the American Academy of Dermatology” Clofazimine may be effective for treating ashy dermatosis.
16 citations
,
October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
30 citations
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October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
37 citations
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November 2002 in “Biology of Reproduction” Prenatal antiandrogen treatment altered hormone levels in adult spotted hyenas, affecting males and females differently.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
10 citations
,
November 1997 in “British Journal of Dermatology” RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
4 citations
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July 2020 in “Research Square (Research Square)” The research helps understand how finasteride works and aids drug development.
9 citations
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November 1997 in “British Journal of Dermatology” 23 citations
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February 2010 in “European Journal of Medicinal Chemistry” 
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
29 citations
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October 1988 in “Journal of Steroid Biochemistry” Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
1 citations
,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
30 citations
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August 1984 in “Archives of Dermatology” Antiandrogen therapy, like cyproterone acetate, effectively treats acne, hirsutism, and hair loss.
20 citations
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May 2011 in “Cancer Biology & Therapy” Finasteride may improve prostate cancer treatment outcomes.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
38 citations
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October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
7 citations
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January 2022 in “Plants” Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.
5 citations
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January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” The treatment reduced hair growth and testosterone in women with excess hair and had some effects on stress responses.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Tectona grandis leaves may help treat hair loss and inflammation.
7 citations
,
May 1977 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” Antiandrogen treatments can help with various women's health issues but often require ongoing use.
5 citations
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July 2021 in “medRxiv (Cold Spring Harbor Laboratory)” Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
Antiandrogens might help prevent or treat COVID-19 by blocking the virus's entry into cells.
9 citations
,
January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
June 2013 in “Vestnik dermatologii i venerologii” Women with hair thinning have disrupted steroid hormone levels, but this doesn't often show as other health issues. More research is needed on hormone balance in this condition.
9 citations
,
July 2021 in “Essays in Biochemistry” Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
December 1976 in “PubMed” Androgens affect skin conditions like acne and hirsutism, treatable with hormone therapy and other methods.
80 citations
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January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
16 citations
,
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills can help reduce mild to moderate acne in women.