research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
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research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
Sex hormones affect brain injury differently in males and females.
research Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research Clomiphene citrate rescue of spermatogenesis in men with infertility while remaining on finasteride: A case report
Clomiphene citrate improves fertility in men taking finasteride for hair loss.
research HAIR REGROWTH
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Metabolic dysfunction in female mice with disruption of 5α-reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice
17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.
research Hair Restoration
The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
research Ovarian hormones and adrenal androgens during a woman's life span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research Role of Nutrition in the Management of PCOS
A balanced diet and healthy lifestyle help manage PCOS symptoms.
research The effects of oestrogens on linear bone growth
Oestrogens are key for bone growth during puberty in both boys and girls.
research Estrogens and aging skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Emerging medication for the treatment of male hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Revising the role of the androgen receptor in breast cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
research Chapter 17. Selective androgen receptor modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Pattern Alopecia during Hormonal Anticancer Therapy in Patients with Breast Cancer
Some breast cancer patients on hormonal therapy may develop male or female pattern hair loss, which can sometimes be improved with topical treatments.
research Polycystic ovary syndrome: diagnosis and management of related infertility
Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity
Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
research A Connection between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin
DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
research A Clinical Study of the Effects of Finasteride on Androgenetic Alopecia
Finasteride effectively treats hair loss in men with minimal side effects.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research CLINICAL UPDATES IN HAIR
Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
research A Mouse Model of Androgenetic Alopecia
Mice with human gene experienced hair loss when treated with DHT.