research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
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research Hairless: A nuclear receptor corepressor essential for skin function
The Hairless gene is crucial for healthy skin and hair growth.
research The Role of 5αR Inhibitors in the Early Growth of Pca Cells
5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.
research Mosaic Hair Regrowth Pattern of Ophiasis and Androgenic Alopecia in a Patient With Alopecia Areata Totalis
The patient with total hair loss did not regrow hair despite treatment, indicating a poor outlook for this type of hair loss.
research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype
Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
research Pharmacokinetics and Bioconversion of Dehydroepiandrosterone after Application of Dexamethasone in Women with Polycystic Ovary Syndrome
Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
research Current and Future Medical Treatment of Androgenetic Alopecia
Treatments for hair loss vary, but cell-based options may be the future.
research Female pattern hair loss: beyond an androgenic aetiology? Reply from authors
Hair loss in women may have multiple causes, and eyebrow regrowth possible with specific injections.
research Corrections to “Female Pattern Hair Loss and its Relationship to Permanent/Cicatricial Alopecia: A New Perspective”
Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
research GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which are Attenuated by Finasteride
GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Nanotechnology in Dermatology
Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
research 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research Alopecia areata: A review
Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
research Adolescent hair loss
Hair loss in teenagers is hard to treat and lacks a cure, with some treatments available depending on the type of hair loss.
research Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration
Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Secondary cicatricial and other permanent alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus*
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Sequential high‐ and low‐dose systemic corticosteroid therapy for severe childhood alopecia areata
High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
research Genetic basis of polycystic ovary syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Promotion effect of acankoreoside J, a lupane-triterpene in Acanthopanax koreanum, on hair growth
Acankoreoside J from Acanthopanax koreanum may help promote hair growth.
research The profile of steroid hormones in human fetal and adult ovaries
Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.
research Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids
Chronic ethanol increases certain brain receptor levels, influenced by steroids and protein changes.
research Dermatologic Signs and Symptoms of Substance Abuse
Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.
research Eyelash alopecia areata: case series and literature review
Eyelash alopecia areata often goes undiagnosed and can lead to complete eyelash regrowth, especially in younger patients.
research Roles of steroid receptors in the lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Evaluation of a novel dry eye model induced by oral administration of finasteride
Finasteride causes reduced tear flow and severe eye inflammation.