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Individuals with this condition often develop male traits and identities at puberty despite being raised as females.

Adrenarche increases adrenal androgens around age 6, affecting hair growth and development.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

Lower TGFß1 levels help stem cells become beige fat cells.

A new, safer method to make finasteride from progesterone is effective for industrial use.

Eyelid cells share signaling components but differ in pathway activity.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.

Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.

Early-life neurosteroid changes affect adolescent exploration and adult behavior.

Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The EDA pathway plays a key role in bone development by interacting with other signaling pathways.

2-Methoxyestradiol causes cancer cell death by activating specific pathways, but androgens can block this effect.

Neurosteroids may help prevent seizures and slow epilepsy progression.

Seeing trauma causes fear in mice by lowering their natural fear-reducing hormones.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.