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DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

Inflammation in rheumatoid arthritis increases steroid activation in cells, reducing inflammation.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

3βHSD2 is not useful for diagnosing PCOS.

The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

The new LC-MS/MS method is more accurate and reliable than traditional immunoassays for measuring steroids in serum.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Sex hormones, especially androgens, play a key role in causing acne.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Body hair isn't a good substitute for scalp hair in steroid analysis.

Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.