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Keratins in Malayan pangolins vary by region, suggesting scales evolved from the tail towards the head.

A gene mutation in mice causes severe skin disorder similar to a human condition.

Human skin has less GDNF and its receptor with age.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Horse skin has a layered epidermis, a dermis with hair follicles, sweat and sebaceous glands, and is supplied by small arteries.

K14 expression in young rats differs from adults.

Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.

TEDAR is crucial for skin cell differentiation and barrier formation.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Transferrin receptor expression increases iron in mouse skin cells without causing damage.

Harlequin ichthyosis involves abnormal skin cell structures and giant mitochondria, affecting skin and hair.

Melasma skin has more melanin and signs of aging, with strong CK10 expression linked to cell differentiation and aging.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Photodynamic therapy was effective in treating multiple scalp basal cell carcinomas with minimal side effects and good cosmetic results.

CD99 is highly present in certain skin cells and could help treat skin conditions.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

The treatment was ineffective in humans.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

EpiLife® media and younger donor age improve artificial skin model quality.

Glycerol is essential for skin hydration in mice without sebaceous glands.

Fish oil improves skin health in people with diabetes and high cholesterol.

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.