185 citations
,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
164 citations
,
April 2008 in “Cochrane library” Current treatments for alopecia show no significant long-term benefits.
115 citations
,
November 2004 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
86 citations
,
August 2014 in “Journal of The American Academy of Dermatology” To diagnose hair loss, use a systematic approach including history, exams, and tests.
79 citations
,
March 2017 in “Dermatologic clinics” Vitiligo affects overall health and self-esteem, needing more research and awareness.
72 citations
,
July 2014 in “American journal of clinical dermatology” Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.
66 citations
,
December 2003 in “Endocrinology and Metabolism Clinics of North America” Doctors need to be better prepared to assess and treat obesity in patients.
56 citations
,
January 2008 in “Dermatology” Higher iron levels in the blood are not linked to increased hair loss in women.
51 citations
,
November 2005 in “Journal of Medical Primatology” Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.
46 citations
,
August 2019 in “Journal of the European Academy of Dermatology and Venereology” People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.
38 citations
,
April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
37 citations
,
September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
34 citations
,
October 2011 in “Pathology Research International” Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
31 citations
,
February 2016 in “American Journal of Men's Health” Finasteride can cause serious emotional side effects; doctors should check patients' mental health history before prescribing.
28 citations
,
November 2017 in “Skin appendage disorders” The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.
25 citations
,
June 2015 in “Scientific Reports” People with alopecia areata have a higher risk of stroke.
24 citations
,
May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
20 citations
,
July 2013 in “International Journal of Dermatology” Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.
19 citations
,
January 2013 in “Journal of Cutaneous Medicine and Surgery” Alopecia patients struggle with emotions and stress, and improving emotional intelligence may help manage hair loss.
18 citations
,
January 2016 in “Skin appendage disorders” The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
18 citations
,
January 2020 in “Journal of Clinical Research in Pediatric Endocrinology” The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
16 citations
,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.
11 citations
,
July 2022 in “Frontiers in immunology” Cases of alopecia areata and its impact on life quality rose globally, but when adjusted for age, the rates decreased, especially in poorer regions.
11 citations
,
November 2017 in “Electronic physician” Depression severity is not linked to PCOS markers like BMI, insulin resistance, or testosterone levels.
10 citations
,
January 2012 in “International Journal of Trichology” The study found no link between anxiety, vitamin B12, folate, TSH, ferritin, zinc levels, and trichodynia in telogen alopecia patients.
9 citations
,
February 2022 in “Nature communications” Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
5 citations
,
January 2017 in “Clinics in Dermatology” Skin symptoms without a medical cause often reflect psychological stress and are influenced by culture, requiring a team approach for treatment.
5 citations
,
March 2011 in “Journal of pediatric health care” The girl with autoimmune hair loss might regrow hair within a year, and treatments can help but not prevent recurrence; dermatologist referral and corticosteroids are recommended.
4 citations
,
April 2016 in “American Journal of Primatology” Where a rhesus macaque used to live can affect its chances of getting alopecia later in life, and females are more likely to be affected than males.
4 citations
,
July 2001 in “Personality and Individual Differences” Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.