354 citations
,
August 1991 in “Molecular Endocrinology” Human adrenals and gonads have a unique enzyme for steroid hormone production.
252 citations
,
January 1991 in “Electron Microscopy Reviews” 169 citations
,
June 2013 in “Medicine” Understanding skin's structure and function is crucial for grasping skin health and diseases.
126 citations
,
January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
124 citations
,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
82 citations
,
January 2006 in “International review of cytology” Vertebrate skin evolved to be more specialized and complex, especially in land animals.
77 citations
,
May 2017 in “Medicine” Understanding skin structure and function is crucial for grasping skin health and diseases.
76 citations
,
September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
71 citations
,
May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” TTD hair brittleness is caused by multiple structural abnormalities.
70 citations
,
June 1998 in “Polymer” Permanent waving damages hair by disrupting its keratin structure.
69 citations
,
January 1995 in “PubMed” Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
68 citations
,
May 2009 in “Medicine” Understanding skin structure and function is crucial due to its role in health and prevalence of many skin diseases.
67 citations
,
December 1990 in “The journal of cell biology/The Journal of cell biology” Researchers found genes for cysteine-rich proteins that form the protective layer of hair in humans and sheep.
65 citations
,
May 2006 in “Journal of Structural Biology” Hair curliness is due to uneven distribution of different cortices within the hair fiber.
61 citations
,
April 2007 in “Journal of Pharmaceutical Sciences” Different forms of hair loss drug can improve effectiveness.
51 citations
,
September 2012 in “Biomacromolecules” Disulfide bonds make keratin in hair stronger and tougher.
49 citations
,
May 2021 in “Medicine” Understanding skin, hair, and nails is crucial due to their complexity and impact on health.
46 citations
,
August 1977 in “Journal of Morphology” The big-clawed shrew's sinus hair follicles are highly specialized for sensing vibrations.
44 citations
,
February 2021 in “Scientific Reports” Mutations in the spike protein affect drug binding and effectiveness.
40 citations
,
September 2004 in “Biomacromolecules” The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.
31 citations
,
February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.
30 citations
,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
28 citations
,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
28 citations
,
January 2016 in “RSC Advances” A non-toxic formula using polycarboxylic acids strengthens and improves hair.
28 citations
,
August 1992 in “Differentiation” A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
27 citations
,
August 2016 Understanding skin structure and function is key to managing skin diseases and improving quality of life.
24 citations
,
November 1978 in “Biochemistry” α-type filaments in guinea pig hair follicles have unique structural features.
23 citations
,
April 2003 in “Journal of Structural Biology” Keratin structure changes during keratinization, but the exact model remains uncertain.
22 citations
,
January 2006 in “Journal of Structural Biology” Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
20 citations
,
February 2017 in “European journal of pharmaceutical sciences” The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.