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A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.

The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.

RNase L suppresses regeneration in mammals.

A girl with skin rashes and low zinc levels improved with zinc supplements and had new gene mutations linked to her condition.

Epiprofin helps cells grow in developing teeth, hair, and limbs.

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

The QuantAnts machines can find cancer markers and create CRISPR targets for them.

Ptprq has multiple forms that change during inner ear development.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

Ablative fractional laser treatment nearly matches the gene reduction effects of topical vismodegib in skin cancer.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Too much Sonic Hedgehog protein stops hair growth in embryos.

Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

ZNF750 and MPZL3 are important in causing seborrheic dermatitis.

Keratin mutations may cause scarring alopecia by damaging hair structure.

Proteomic analysis can identify genetic differences in mouse hair, helping understand hair defects and variations.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Male mice with FGF5 mutations grow longer hair than females.

Monilethrix is linked to the type II keratin gene on chromosome 12q13.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

PTCH gene mutations contribute to basal cell carcinoma development.

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Peficitinib can turn human fibroblasts into cells that help grow hair.