research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
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research Targeted radionuclide therapy for head and neck squamous cell carcinoma: a review
Targeted radionuclide therapy shows promise for improving head and neck cancer treatment but needs more research.
research Association of Spironolactone Use With Risk of Cancer
Spironolactone does not increase cancer risk and may lower prostate cancer risk, but more research is needed.
research Design, Development, and Optimization of Spanlastics for Delivery of Rizatriptan Benzoate
Spanlastics effectively deliver Rizatriptan Benzoate with high efficiency and controlled release.
research EFECTO DE LA TESTOSTERONA, 4-HIDROXIANDROSTENDIONA Y FINASTERIDE SOBRE LA HEMOSTASIA EN UN MODELO DE ISQUEMIA/REPERFUSION CORONARIA EN RATA
Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.
research Treatment of hirsutism with spironolactone
Spironolactone is effective and safe for treating excessive facial hair in women.
research A prospective randomized trial comparing finasteride to spironolactone in the treatment of hirsute women
research A comprehensive investigation into the molecular mechanism responsible for selective androgen receptor (SARM) tissue-selectivity
SARMs work differently in tissues due to unique interactions and structures.
research Design and synthesis of novel Azasteroids and Pseudoazulenyl nitrones
The research created new azasteroids and pseudoazulenyl nitrones, which could be useful in medicine.
research Femoral Neck Stress Fracture Complicated by Deep Venous Thrombosis and Complex Regional Pain Syndrome: A Case Report
A multidisciplinary approach is crucial for treating stress fractures and related complications in athletes.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Biochemical and Histopathological evaluation of prostatic tissue under effect of Pterostilbene in benign prostatic hyperplasia rat model
Pterostilbene significantly reduces prostate enlargement and has strong antioxidant effects.
research Androgens
research OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants
OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
research Thallium
Thallium exposure can cause serious health issues, including nerve damage and hair loss.
research A Case of Satoyoshi Syndrome: A Multisystem Disorder
Steroid treatment greatly improved the symptoms of a boy with a rare disorder called Satoyoshi syndrome.
research A comparative analysis of three explanatory models of mental disorder and a preferred focus of explanation
Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.
research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects
Increasing TSPO in the brain reduces anxiety and depression.
research Avaliação da estabilidade da Finasterida, estudos de compatibilidade fármaco-excipientes e controle de qualidade das formulações farmacêuticas sólidas do mercado
Finasteride is stable except in high pH, and lactose and magnesium stearate should be replaced in formulations.
research Establishment of Tsc2-deficient rat embryonic stem cells
Tsc2-deficient stem cells can help understand and treat TSC-related tumors.
research Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen–glucose deprivation
Progesterone protects rat brain cells by enhancing GABA A receptor activity.
research Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep
Reducing neurosteroid levels worsens brain injury in fetal sheep.
research Spironolactone in the Treatment of Hirsutism
Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.
research ROS and calcium oscillations are required for polarized root hair growth
ROS and calcium oscillations are essential for root hair growth in plants.
research Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques
research A Novel Hair Analysis for Trace Elements on Hair Cross Section by Synchrotron Radiation X‐Ray Fluorescence Imaging with X‐Ray Microprobe: Two‐Dimensional Distribution of Lead and Zinc on Smelter Hair
The method effectively maps lead and zinc in hair, aiding understanding of heavy metal exposure risks.
research Quality of Calcium Food Supplements: Evaluation Compared to Manufacturers’ Declarations
Some calcium supplements have more calcium than their labels say, and a few have less.
research Dihydrotestosterone induces arterial stiffening in female mice
Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
research Soft-tissue calcification in systemic lupus erythematosus
Soft-tissue calcification is rare in systemic lupus erythematosus.
research On Photo-Stability of Oxybenzone
Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.