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March 2003 in “The journal of small animal practice/Journal of small animal practice” Trilostane helped a dog with an adrenal tumor feel better and stay healthy.
21 citations
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October 2023 in “The Journal of Physical Chemistry C” Phosphates strongly attach to cerium dioxide nanoparticles, showing specific spectral patterns.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Spironolactone for skin issues rarely causes low blood pressure.
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April 2020 in “Journal of The American Academy of Dermatology” Spironolactone effectively treats female pattern hair loss with few side effects.
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June 1986 in “Journal of Clinical Pharmacy and Therapeutics” Metal binding to sodium valproate may be linked to hair loss in epilepsy patients.
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April 2001 in “Bioorganic & Medicinal Chemistry Letters” The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
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May 2020 in “Arthritis research & therapy” DHT inhibition may increase spinal bone growth in ankylosing spondylitis.
Spironolactone is a promising alternative to antibiotics for treating acne in adult females.
31 citations
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February 1972 in “Experientia” The diphosphonate was the most effective at preventing calcification in rats.
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April 2011 in “PubMed” Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
January 2010 in “Guoji yaoxue yanjiu zazhi” Thallium poisoning is serious, affecting nerves and organs, and is treated by reducing absorption and removing it from the body.
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September 2020 in “Actas Dermo-Sifiliográficas” January 2011 in “Clinical Cosmetic and Investigational Dermatology” Spironolactone is a safe and effective hair loss treatment, especially with minoxidil.
18 citations
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May 2020 in “Biomolecules” Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
April 2021 in “Journal of Investigative Dermatology” Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
13 citations
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November 2005 in “Epilepsia” Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
December 1963 in “Bulletin of Experimental Biology and Medicine” Radioiodine-131 significantly accumulates in skin and hair.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” A new accurate and reliable method was developed to measure Spironolactone and Hydrochlorothiazide together in medicines.
1 citations
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May 2019 in “The Journal of Sexual Medicine” Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.
19 citations
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June 1999 in “Steroids” Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
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May 2003 in “Expert Opinion on Therapeutic Patents” Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
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June 2015 in “Australasian Journal of Dermatology” Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.
38 citations
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October 2005 in “Expert opinion on therapeutic patents” Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
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January 2018 in “General Physiology and Biophysics” The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
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November 2016 in “Aaps Pharmscitech” Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
October 2022 in “British Journal of Dermatology”