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Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures

60 citations , December 2013 in “PLoS ONE”

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

60 citations , November 2013 in “Development”

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

research c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

60 citations , February 2013 in “Cell reports”

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Clinical, Metabolic, and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, and Placebo-Controlled Trial

research Clinical, metabolic, and endocrine parameters in response to metformin and lifestyle intervention in women with polycystic ovary syndrome: A randomized, double-blind, and placebo control trial

60 citations , February 2010 in “Gynecological Endocrinology”

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation

60 citations , January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

Applying a specific inhibitor lightens skin and hair color.

research Cardiovascular risk factors in young Czech females with polycystic ovary syndrome

60 citations , April 2003 in “Human Reproduction”

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling

59 citations , April 2016 in “Cell Reports”

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

research Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer

59 citations , April 2016 in “Breast Cancer Research and Treatment”

Targeting vitamin D and androgen receptors may effectively treat triple-negative breast cancer, especially with chemotherapy.

research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice

59 citations , July 2015 in “Journal of Immunology”

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

research Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle

59 citations , January 2015 in “Nanoscale”

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

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