March 2021 in “Annals of Translational Medicine” Two patients with lupus had an unusual type of hair loss not typical for the disease.
26 citations
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May 2019 in “Journal of Multidisciplinary Healthcare” A multidisciplinary approach is essential for effectively managing cutaneous lupus erythematosus.
158 citations
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March 2011 in “Journal of the American Academy of Dermatology” Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.
8 citations
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February 2022 in “Frontiers in Medicine” COVID-19 may trigger severe skin flare-ups in people with autoimmune conditions like lupus.
2 citations
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December 2019 in “The Open Dermatology Journal” Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.
1 citations
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February 2025 in “Journal of Drugs in Dermatology” Early and accurate diagnosis is crucial for effectively managing hair loss in lupus and alopecia areata.
39 citations
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May 2019 in “Journal of the American Academy of Dermatology” Hair loss in lupus patients indicates higher disease activity.
8 citations
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August 2021 in “Lupus Science & Medicine” Patients with cutaneous lupus are most concerned about self-consciousness, physical symptoms, and disease progression.
4 citations
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January 2015 in “Case Reports in Rheumatology” Early recognition and management of connective tissue diseases like lupus are crucial in young patients.
October 2025 in “Scholars Journal of Medical Case Reports” Intralesional corticosteroids effectively treat scalp Discoid Lupus and restore hair.
20 citations
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June 2021 in “British Journal of Dermatology” Use antimalarials like hydroxychloroquine for cutaneous lupus, avoid herbal supplements, and focus on lifestyle changes like sun protection.
17 citations
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July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.
3 citations
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June 2020 in “Cureus” A woman's hair loss led to discovering she had lupus.
May 2026 in “Mayo Clinic Proceedings” Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease primarily affecting women of reproductive age, characterized by multisystem involvement and significant morbidity. The document emphasizes the importance of early diagnosis and intervention, particularly when ANA positivity is accompanied by inflammatory features. Key management strategies include using hydroxychloroquine as foundational therapy, minimizing glucocorticoid use, and addressing comorbidities like cardiovascular disease and osteoporosis. Routine monitoring for lupus nephritis and other organ-specific manifestations is crucial. The document highlights the need for coordinated care between rheumatology and other clinicians to improve patient outcomes, noting disparities in outcomes across different racial and ethnic groups. Despite advances, SLE patients face increased risks of kidney failure, cardiovascular disease, and premature mortality.
A patient with patchy hair loss was successfully treated for Tumid Lupus Erythematosus after other treatments failed.
Scalp lesions in discoid lupus are more common in women and linked to other autoimmune diseases.
SLE should be considered in unexplained fevers, even in males.
9 citations
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September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
6 citations
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April 2021 in “Frontiers in Immunology” A patient with lupus and long-term hair loss saw significant hair regrowth after using the drug tofacitinib.
1 citations
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May 2025 in “The Journal of Rheumatology” Anifrolumab effectively improved lupus headaches in a patient unresponsive to other treatments.
November 2024 in “Deleted Journal” Platelet-rich plasma injections can help treat hair loss in lupus patients.
February 2024 in “Rheumatology & autoimmunity” Lupus can cause unusual vision problems, so it's important to consider it in such cases.
January 2024 in “Pan African Medical Journal” Non-scarring hair loss is common in lupus patients and can be diagnosed with specific hair and tissue tests.
11 citations
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September 2022 in “The Journal of Rheumatology” Skin problems are common in lupus patients and should be treated early to prevent worsening.
227 citations
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November 2004 in “Medicine” Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.
1 citations
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January 2022 in “Skin Appendage Disorders” Lupus erythematosus can mimic alopecia areata, and trichoscopy is key for accurate diagnosis and better patient outcomes.
2 citations
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February 2020 in “Chinese Medical Journal” Undiagnosed lupus can cause severe complications after epidural anesthesia, leading to muscle weakness and potentially death.
4350 citations
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May 2012 in “Arthritis & Rheumatism” The new SLICC criteria for diagnosing lupus are more sensitive and accurate than the old criteria.
Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.
July 2024 in “Biomolecular and Health Science Journal” Mycophenolic acid effectively improved hair and nail growth in a lupus patient.