research Chronic Selenosis in Dairy Animal - A Study of Clinical Observations and Haematological Profile
High selenium levels in some areas cause health issues in cows and buffaloes, but blood tests remain normal.
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180-210 / 1000+ resultsresearch Long-term toxicity studies on oxidation hair dyes
The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
research Effects of 2-Ethylhexanoic Acid on Reproduction and Postnatal Development in Wistar Rats
2-Ethylhexanoic acid harms fertility and delays development in rats.
research Modeling of chronic radiation-induced cystitis in mice
Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
research Haematological analysis on sub acute oral toxicity study of water extract from leaves of hibiscus rosa sinensis l. in Balb/C mice
Hibiscus rosa-sinensis leaf extract is safe for mice at tested doses.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research Acute and Long-term Toxicity of Cyclophosphamide
Cyclophosphamide can cause serious short-term and long-term side effects, including increased cancer risk and infertility.
research Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine
research Chemotherapy-induced toxicity—a secondary effect caused by released DNA?
Chemotherapy toxicity might be reduced by using DNA neutralizing agents.
research Developmental and reproductive outcome of F1 generation of Wistar rats exposed to Acanthus montanus aqueous extract during organogenesis
Acanthus montanus extract harms fetal development and causes infertility in offspring.
research Zone 1 Hepatocellular Necrosis: A Manifestation of Selenium Toxicity?
Excessive selenium intake can cause liver damage.
research Beneficial Effects of Liver on Cortisone Acetate Toxicity in the Rat.
Liver in the diet reduces cortisone acetate toxicity effects in rats.
research Two-year follow-up of two patients after severe thallium intoxication
Hair loss and polyneuropathy improved, but severe vision impairment persisted.
research Changes in intraepidermal nerve fiber and Langerhans cell densities in the plantar skin of rats after mercuric chloride exposure
Mercury exposure damages small nerve fibers in rats' skin.
research Thallium
Thallium exposure can cause serious health issues, including nerve damage and hair loss.
research Histological Study of the Damaging Effect Induced by Cyclophosphamide on Intestinal Mucosa of Adult Male Albino Rat
Cyclophosphamide severely damages the intestinal lining in rats.
research First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
research Antitumour and toxic effects on Wistar rats of two new platinum complexes
The new platinum complexes effectively increased survival in rats with tumors, despite some reversible side effects.
research Studies of the components of an oral contraceptive agent in albino rats. II. Progestogenic component and comparison of effects of the components and the combined agent
High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
research Problems in evaluating chronic toxicity of contraceptive steroids in dogs
High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
research Regression of Pathologic Changes Induced by the Long-term Administration of Contraceptive Steroids to Rodents
Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.
research TOXICOLOGICAL STUDY ON THE HEALTH EFFECTS OF LONG TERM EXPOSURE TO BENZENE IN BENZENE FILLING WORKERS, QASSIM REGION, KSA
Long-term exposure to benzene increases skin diseases, blood disorders, and liver problems.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics after γ and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research A Case Report on Iatrogenic Methotrexate Toxicity
Early recognition of methotrexate toxicity symptoms is crucial.
research Cutaneous Lesions in the Rat Following Administration of an Irreversible Inhibitor of erbB Receptors, Including the Epidermal Growth Factor Receptor
CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.
research Resesrch of Xiaochuang Drink on Rabbit Ear Micro Acne Model and Its Acute Toxicity Experiment
Xiaochuang Drink effectively treats rabbit ear acne and is safe at clinical doses.
research Where is the data? Delayed and chronic irAE surveillance and management after cessation of ICIs: expert insights from SITC on survivorship care and the need for long-term data
Long-term data and a team approach are needed to manage chronic side effects from cancer treatments.
research Post-Drug Syndromes: A Neglected Challenge in Pharmacovigilance and Public Health
Current drug safety systems fail to detect long-term side effects, leading to preventable health issues.
research ASSOCIATION OF SYSTEMIC LUPUS ERYTHEMATOSUS AND CHRONIC GRANULOMATOUS DISEASE IN ADULTS: REPORT OF 2 CASES
Chronic granulomatous disease may be linked to developing systemic lupus erythematosus.
research Lead, Mercury, and Arsenic Poisoning Due to Topical Use of Traditional Chinese Medicines
Traditional Chinese medicines with heavy metals can cause severe poisoning.