51 citations
,
May 2021 in “Nature Communications” High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
3 citations
,
January 1984 20 citations
,
July 1987 in “Development Genes and Evolution”
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The STRIPAK complex is crucial for skin cell organization and creating a functional skin barrier.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
11 citations
,
July 2022 in “International Journal of Molecular Sciences” Tight junctions help control skin shedding and may be targets for treating certain skin conditions.
April 2021 in “Journal of Investigative Dermatology” Early-stage skin substitutes improve wound healing and skin structure.
36 citations
,
January 1994 in “Cell and Tissue Research” 189 citations
,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
17 citations
,
August 2014 in “The Anatomical Record” Scaffoldin helps form hard skin structures in chicken embryos.
September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
5 citations
,
February 2014 in “PloS one” Eyelid cells share signaling components but differ in pathway activity.
13 citations
,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
50 citations
,
September 1997 in “Developmental Biology” 7 citations
,
November 1997 in “Reproduction Fertility and Development” Epidermal growth factor disrupts hair and gland formation in bandicoots.
April 2023 in “Journal of Investigative Dermatology” Ectomesenchyme is a key source of skin stem cells.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
9 citations
,
May 2013 in “European Journal of Dermatology” Dermoscopy can non-invasively detect eruptive vellus hair cysts on the labia majora.
7 citations
,
September 2014 in “Journal of the American Academy of Dermatology” Dermoscopy helps accurately diagnose and treat epidermal cysts.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
54 citations
,
January 1984 in “Molecular and Cellular Biochemistry” 42 citations
,
September 1990 in “Journal of Investigative Dermatology” 4 citations
,
October 2004 in “Humana Press eBooks” Epidermal growth factor stops hair follicle formation in developing mouse skin.
1 citations
,
January 1984 96 citations
,
December 1995 in “Journal of Investigative Dermatology”
115 citations
,
February 2016 in “Nature Communications” Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
8 citations
,
January 2012 in “Dermatology Research and Practice” New subcision technique with a bent needle and syringe improves ease, effectiveness, and comfort for treating acne scars.
22 citations
,
May 2007 in “Molecular Biotechnology” 65 citations
,
December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.