research Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. rigida Esper
A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
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research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures
EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
research The efficacy and safety of valproic acid medications with controlled active ingredient release in adults in real clinical practice from the position of pharmacokinetic and pharmacogenetic approaches
Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.
research Drug Repurposing Patent Applications July–September 2025
New drug uses show promise but need more research.
research Hair extensions: a concerning cause of hair disorders
Hair extensions can cause hair loss and scalp damage, and these problems might be more common than people realize.
research Evaluation of hair loss
Detailed patient history and physical exams are crucial for diagnosing hair loss.
research Practical contact dermatitis
The book "Practical Contact Dermatitis" is useful for dermatologists but could be more user-friendly.
research Abortion
The book provides a historical view of abortion in the U.S., critiques the pro-choice movement, and recommends including abortion in medical education.
research Liquid Protein Diets and Telogen Effluvium: A Case Report
A liquid protein diet caused hair loss in a young woman.
research History and physical examination of polycystic ovary syndrome: Detecting too much or too little
The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
research Regaining Control Over Cancer: A Health Communication Initiative Documenting Complementary and Alternative Medicine Use Among Cancer Patients and Survivors
Patients should discuss complementary medicine use with doctors to improve health outcomes.
research Acne fulminans: explosive systemic form of acne
Taking finasteride daily can effectively and safely increase hair density and thickness for women with hair loss.
research Commentary
Hair disease research is a growing and evolving field in dermatology, with recent significant advances.
research Psychiatry, Medicine
Abortion access should be defended on public health grounds, and medical evaluations are crucial in psychiatric cases to avoid misdiagnosis.
research Dictionary
Both books are valuable resources in their fields.
research Health Messages
The document reviewed various health-related books, focusing on abortion debates, medical conditions, and effective health communication.
research Surgery of the Skin
The book details advanced techniques in cosmetic dermatology for experienced surgeons.
research BOOK REVIEWS
The document concludes that "Photodamage" and "Photoimmunology" are valuable resources, while "Pediatric Dermatopathology" and "Hair and Scalp Disorders" have limitations.
research Regulatory pathways implicated in male androgenetic alopecia pathogenesis
Genes controlling hair growth and immune response are disrupted in male pattern baldness.
research Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research [The treatment of epilepsies with Convulsofin].
Convulsofin effectively treats primary epilepsy but has some side effects.
research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome
DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.
research Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor.
Four-amino acid part makes enzyme sensitive to finasteride.
research Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway
Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.
research Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle
TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.
research PD05-05 SINGLE CENTRE EXPERIENCE OF CHELATING AGENTS IN CYSTINURIA
Both penicillamine and tiopronin have significant side effects, but trying the alternative drug can be beneficial if the first is not tolerated.
research Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists
Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
research Transcranial focused ultrasound-mediated unbinding of phenytoin from plasma proteins for suppression of chronic temporal lobe epilepsy in a rodent model
Using focused ultrasound on the brain can help epilepsy medicine work better in rats.