research Disrupted citric acid metabolism inhibits hair growth
Disrupted citric acid metabolism stops hair growth.
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research The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions
Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.
research Design and synthesis of novel Azasteroids and Pseudoazulenyl nitrones
The research created new azasteroids and pseudoazulenyl nitrones, which could be useful in medicine.
research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
research Corrigendum: Stimulation of hair regrowth in an animal model of androgenic alopecia using 2-deoxy-D-ribose
The correction does not change the conclusion that 2-deoxy-D-ribose helps hair regrowth.
research Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans
The hr gene is crucial for skin and hair health, with mutations causing hair disorders.
research The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm
The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients
Equisetum debile extract may help with hair loss by inhibiting enzymes and reducing inflammation.
research Preparation of finasteride by selective dehydrogenation using IBX
The method produces finasteride with a 92% yield.
research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
The document reviews the advancements and potential of peptide-based PROTACs (pPROTACs) in targeted protein degradation, emphasizing their ability to target "undruggable" proteins and offering advantages over small-molecule PROTACs. Recent innovations, such as improved cell permeability, stability, and modular design, enhance their therapeutic potential, particularly in cancer therapy and other medical applications. Strategies like self-assembling pPROTACs and bioPROTACs expand their design space, while integration with technologies like AI-driven design and nanotechnology promises further enhancements. Despite challenges in delivery and stability, pPROTACs are poised to become versatile platforms in precision medicine, with ongoing research supported by multiple institutions and grants.