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The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Finasteride, a drug used for anti-hyperplasia, can be effectively delivered in the form of matrix tablets.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.

Androsterone and finasteride have different solid forms, with new findings correcting previous errors and identifying a new form.

New treatments targeting fibrosis could improve urinary symptoms in BPH.

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

Clove oil and grape seed extract increase finasteride skin absorption, while urea decreases it.

Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.

Espumil foam base allows easy preparation of skin medications for hairy areas.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Dual therapy with specific medications can help manage male urinary symptoms and reduce side effects.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

A new method to make finasteride for hair loss treatment was developed.

Patients follow treatment well, but many change medicines; good information helps compliance.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.

Curcumin-based polyurethanes with more PEG improve curcumin release and maintain strong antioxidant and antibacterial properties.

Dapagliflozin improved blood sugar control in a man with Werner syndrome without side effects.

Managing malignant ureteral obstruction is challenging and requires personalized treatment to protect kidney function and patient health.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Thiourea compounds affect hair growth and pigmentation in black rats.

Cinnamic acid in hydrogels can effectively fight fungi but spreads less than in solution.

Combination drug therapies are more effective for high-risk BPS patients but have more side effects and costs.

UHP-sCESr is as effective as HESr for treating BPH symptoms.

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.