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The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

CSLD1 suppresses rice root hair growth with NH4+ and regulates AMT1;2 expression.

Certain genetic variations are linked to hair loss in Mexican men.

Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.

Steroid sulfatase in hair follicles may be a target for treating hair loss.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.

Sulfur-35 can be used to track hair growth and past exposure.

Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.

SSO helps in skin protection and keratinization.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

CCC1 is essential for ion balance and proper plant cell function.

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

A TNFAIP3 gene mutation can cause unusual and varied symptoms of lupus and Sjogren's syndrome.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.

A rare gene variant causes sexual development issues in siblings, needing personalized treatment.