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Cis-UCA can form new compounds without enzymes, and sulphide donors reduce its UVB-induced toxicity in skin cells.

Effective treatment for UFT overdose includes antibiotics and G-CSF, with bone marrow biopsy and transfusion as backup options.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

Altering SSAT affects fat metabolism and body fat in mice.

Minoxidil boosts hair growth in genetically modified mice.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.

Alternating treatment with two drugs could help cells in a rapid aging disease.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Transamidases are present in the epidermis but their exact role is unclear.

The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.

A 7-year-old girl was diagnosed with trichothiodystrophy due to low sulfur levels in her hair.

Low-sulfur hair syndrome can cause UVB sensitivity and testicular failure.

Increasing TSPO in the brain reduces anxiety and depression.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Selenium therapy improved health in cystic fibrosis patients with fewer side effects at a lower dose.

Trichothiodystrophy is a condition with brittle hair and various physical and mental issues due to low sulfur in proteins.

Mice hair follicles take in the amino acid cystine.