13 citations
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May 1996 in “Archives of Disease in Childhood” Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
1 citations
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March 2023 in “Phytochemistry Reviews” CBD may improve skin and hair health, but its effective use and safety need more research.
11 citations
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June 2024 in “Molecules” Alpinia zerumbet has different medicinal properties in its parts due to varying chemicals.
April 2026 in “Nanomaterials” The document explores the potential of plant-derived extracellular vesicles (PDEVs) from Ayurvedic medicinal plants as a modern approach to delivering bioactive compounds with enhanced stability and targeted uptake. PDEVs offer advantages such as easy isolation, low cost, and safety, and they can transport therapeutic agents to enhance bioavailability and target damaged cells. The review highlights the synergy between traditional Ayurvedic medicine and modern nanomedicine, proposing PDEVs as a bridge between the two. Notably, garlic-derived exosomes have shown efficacy in promoting hair growth through the Wnt/β-Catenin pathway, while Ashwagandha-derived exosome-like nanoparticles significantly promote human hair growth by stimulating VEGF-A production. The document emphasizes the need for further research and standardization of isolation techniques to fully realize the therapeutic potential of PDEVs in treating conditions like hair loss, cancer, and inflammatory diseases.
35 citations
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November 2021 in “Journal of nanobiotechnology” Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
17 citations
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January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
January 2017 in “Journal of Dermatology and Venereology” Naringenin and Hesperetin may help hair grow and protect hair cells from damage.
1 citations
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September 2023 in “Molecules (Basel. Online)” Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
15 citations
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October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
15 citations
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
8 citations
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February 2025 in “Pharmaceuticals” Polyphenols may help treat skin diseases due to their anti-inflammatory and antioxidant effects.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
2 citations
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January 2019 in “Annals of Dermatology” Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
1 citations
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September 2023 in “Applied sciences (Basel)” Ishige sinicola extract may help prevent muscle atrophy through its antioxidant and anti-inflammatory effects.
November 2022 in “Frontiers in pediatrics” A girl with skin rashes and low zinc levels improved with zinc supplements and had new gene mutations linked to her condition.
20 citations
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November 1968 in “The Lancet” Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.
29 citations
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September 1990 in “Biochemical Journal” Enzyme purified and characterized for minoxidil sulphation in rat liver.
58 citations
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January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
50 citations
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December 1999 in “British Journal of Dermatology” Finasteride improves hidradenitis suppurativa but not for child-bearing women.
46 citations
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May 2009 in “Maturitas” Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
January 2020 in “Cosmetics” Ecklonia cava extract may protect the scalp from pollution and improve its health.
220 citations
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August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
82 citations
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August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
74 citations
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May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
59 citations
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February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
48 citations
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January 2018 in “Scientific Reports” Hair analysis can reveal metabolic changes and potential pregnancy complications.
47 citations
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March 2004 in “European journal of endocrinology” Spironolactone plus finasteride reduces hirsutism more effectively.
21 citations
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September 2011 in “Journal of Pharmaceutical Sciences” Desolvation of finasteride depends on environment and technique.
2 citations
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April 1981 in “International Journal of Dermatology” No treatment reliably changes Alopecia Areata's course; reassurance and possibly a wig are recommended.
October 2001 in “WORLD SCIENTIFIC eBooks” Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.