53 citations
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October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
52 citations
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February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
52 citations
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October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
51 citations
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September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
51 citations
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March 2014 in “Nature Communications” Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
49 citations
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June 2009 in “Seminars in Cutaneous Medicine and Surgery” The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.
49 citations
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February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
47 citations
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February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
47 citations
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December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
47 citations
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
47 citations
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March 2016 in “Journal of dermatology” Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.
47 citations
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September 2015 in “Journal of Drug Delivery Science and Technology” Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
47 citations
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July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
46 citations
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January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
44 citations
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March 2012 in “Fitoterapia” Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” Scientists created tiny particles that release medicine on the skin and in hair, working better at certain pH levels and being safe for skin cells.
42 citations
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May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
41 citations
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November 2024 in “Molecular Biomedicine” Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
41 citations
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August 2024 in “Drug Delivery and Translational Research” 3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
41 citations
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July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
40 citations
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” Changes in keratin make hair follicles stiffer.
40 citations
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December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.
39 citations
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
39 citations
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June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” Plant-based ingredients are effective and safe for modern skincare products.
38 citations
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July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.