36 citations
,
October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
33 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
22 citations
,
January 2014 in “Biological & Pharmaceutical Bulletin” Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.
14 citations
,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
13 citations
,
July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
11 citations
,
December 2011 in “Revista Brasileira de Farmacognosia” The seeds of Abrus precatorius, when processed, can prevent hair loss more effectively than common treatments.
10 citations
,
April 2000 in “Archives of Oral Biology” Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
8 citations
,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
4 citations
,
January 2012 in “Medical Hypotheses” Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
2 citations
,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
1 citations
,
January 2015 in “Hair therapy & transplantation” Some supplements and hormones can increase hair loss by raising DHT levels.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
October 2023 in “International journal of biology, pharmacy and allied sciences” Personalized treatment plans combining natural and synthetic approaches are important for managing alopecia effectively.
January 2023 in “Journal for ReAttach Therapy and Developmental Diversities” Carthamus oxyacantha may help treat BPH by inhibiting 5α-reductase.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
November 1999 in “Journal of Cutaneous Medicine and Surgery” Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
112 citations
,
October 2005 in “Mayo Clinic Proceedings” Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
22 citations
,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
21 citations
,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
7 citations
,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
3 citations
,
February 2019 in “Journal of Cosmetic Dermatology” The effects of estrogen on human scalp hair growth are unclear and need more research.
1 citations
,
December 2021 in “Androgens” Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
January 2026 in “Clinical Chemistry and Laboratory Medicine (CCLM)” The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.
September 2025 in “International Journal of Innovative Technologies in Social Science” Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
122 citations
,
July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
110 citations
,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.