December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
25 citations
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December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
Deucravacitinib improves symptoms and reduces inflammation in Lichen Planopilaris.
421 citations
,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
291 citations
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January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” No single treatment is consistently effective for alopecia areata, and more research is needed.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
59 citations
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June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
52 citations
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March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
41 citations
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February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
34 citations
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October 2011 in “Pathology Research International” Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
28 citations
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January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
23 citations
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March 2001 in “Clinics in dermatology” Alopecia areata involves immune response and gene changes affecting hair loss.
23 citations
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July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
16 citations
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March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
16 citations
,
April 2007 in “Journal of Medical Primatology” The monkey's hair loss was due to an autoimmune disease, not genetics.
15 citations
,
July 2002 in “Australasian Journal of Dermatology” Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
8 citations
,
December 2008 in “Journal of The American Academy of Dermatology” Finasteride can cause a unique skin reaction on the penile shaft.
5 citations
,
July 1991 in “Irish Journal of Medical Science (1971 -)” Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
4 citations
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May 2025 in “Frontiers in Immunology” JAK inhibitors effectively and safely treat alopecia areata with few serious side effects.
4 citations
,
September 2017 in “Skin appendage disorders” The dog with an Alopecia Areata-like condition showed signs of an autoimmune disease and partially regrew hair without treatment, suggesting dogs could be models for human AA research.
3 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ILC1 cells contribute to hair loss in alopecia areata.
2 citations
,
February 2014 in “Hair therapy & transplantation” Alopecia Areata is an autoimmune condition causing hair loss, influenced by genetics, environment, and possibly improved by anti-MIF therapy, with many patients experiencing regrowth within a year.
February 2026 in “Journal of Allergy and Clinical Immunology” Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
January 2026 in “Scientific Reports” PCOS involves immune and genetic factors, with key roles for T cells and specific genes.
Pvalb8 is essential for zebrafish hearing and hair cell development, and its mutation causes hearing loss.
May 2025 in “The Journal of Rheumatology” Chronic granulomatous disease may be linked to developing systemic lupus erythematosus.
January 2025 in “American Journal of Translational Research” Erianin may effectively treat alopecia areata by targeting the immune system.