5 citations
,
January 2022 in “PloS one” Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
Dexamethasone-primed stem cell media shows promise in treating lupus by reducing symptoms and inflammation.
January 2024 in “Journal of Natural Remedies” Solanum nigrum extract may help regrow hair.
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
April 2012 in “Informa Healthcare eBooks” Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.
12 citations
,
August 2001 in “PubMed” CE-PTG is a better method for analyzing hair growth in androgenetic alopecia.
15 citations
,
February 2003 in “British Journal of Dermatology” The study suggests computer-assisted analysis of scalp biopsies could improve hair loss diagnosis but needs more validation.
2 citations
,
August 2006 in “Journal of Dermatological Science” Automated image analysis helps diagnose and monitor alopecia areata by efficiently measuring hair follicles.
328 citations
,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
2 citations
,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” The most effective way to diagnose non-scarring hair loss is by transverse sectioning, and some cases, particularly in males with inflammation around hair follicles, might be curable.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
128 citations
,
January 1996 in “Journal of analytical toxicology.” Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
47 citations
,
June 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
17 citations
,
July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
March 2024 in “International journal of molecular sciences” taVNS reduces vitiligo symptoms in mice.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
4 citations
,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
50 citations
,
May 1999 in “Journal of Reconstructive Microsurgery” Microsurgical reconstruction effectively covers complex scalp defects but doesn't improve survival for cancer-related cases.
16 citations
,
May 2013 in “Australasian Journal of Dermatology” Hair loss in Cronkhite-Canada syndrome is reversible by treating the gut issues and doesn't need steroid treatment for the hair itself.
234 citations
,
December 1996 in “Journal of The American Academy of Dermatology” Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.
14 citations
,
December 2013 in “Anais Brasileiros De Dermatologia” A woman with long-term scalp psoriasis developed rare scarring hair loss that didn't fully respond to treatments.
April 2017 in “Australasian Journal of Dermatology” Most patients with Lichen planopilaris improved with acitretin, but treatments often didn't work well; preventing infection in skin surgery is important, and bupivacaine might be a better anesthetic.
14 citations
,
December 2007 in “Pediatric allergy and immunology” Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.
5 citations
,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
Hair restoration surgery has improved to transplant hair in natural groupings, but it's labor-intensive and can't fully restore normal hair density.
7 citations
,
January 2019 in “Dermatology Online Journal” Ustekinumab treatment didn't prevent frontal fibrosing alopecia.
September 2013 in “Hair transplant forum international” The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
73 citations
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January 2002 in “Journal of Investigative Dermatology” Epidermal stem cells don't use gap junctions to communicate.
January 2026 in “Western Journal of Nursing Research” Hair cortisol levels don't reliably indicate chronic stress in people with multiple sclerosis.