research Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
Search
for
Sort by
Research
480-510 / 1000+ resultsresearch Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Hair follicle immune privilege and its collapse in alopecia areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
A holistic approach is crucial for treating skin disorders and restoring barrier function.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research The autoimmune basis of alopecia areata: A comprehensive review
Alopecia areata is caused by the immune system attacking hair follicles.
research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
research Skin manifestations of celiac disease
A gluten-free diet significantly improves skin and health issues in people with dermatitis herpetiformis, a skin condition linked to celiac disease.
research CHRONIC TREATMENT WITH FINASTERIDE DAILY DOES NOT AFFECT SPERMATOGENESIS OR SEMEN PRODUCTION IN YOUNG MEN
Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
research The role of the microbiome in scalp hair follicle biology and disease
The scalp's microorganisms significantly affect hair health and disease.
research Role of janus kinase inhibitors in the treatment of alopecia areata
Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
research Follicular mucinosis: A detailed morphologic and immunopathologic study
Benign follicular mucinosis involves immune cells attacking hair follicles.
research Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection
Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
research Rippled‐pattern trichomatricoma
A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects
3D spheroid culture makes stem cells better at reducing inflammation.
research Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues
Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Alopecia areata after HLA-identical BMT from an affected, sibling donor
Alopecia areata can be transferred through stem cell transplants from affected siblings.
research Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo
Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
research 0037 Inflammatory implications in female pattern hair loss: unraveling B cell-related immune activation through comparative transcriptome profiling
Immune system changes may contribute to female pattern hair loss.
research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders
Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
research Editors’ Picks
A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.
research Androgen metabolism in hirsute patients treated with cyproterone acetate
Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
research Epitestosterone
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research The Effects of Estradiol, Androgens and the Selective Estrogen Modulators: Ospemifene, Raloxifene and Tamoxifen on Explant Cultures of Human Breast Tissue
Including androgens in hormone therapy may lower breast cancer risk.
research The Anti-atopic Lotions Containing Fucoidan Extracted from Ecklonia Cava Impact on Hairless Mice Atopic Dermatitis Skin
Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.
research The Role of Hair Follicle Immune Privilege Collapse in Alopecia Areata: Status and Perspectives
Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Pathomechanisms of immune-mediated alopecia
The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.