80 citations
,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
77 citations
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April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
26 citations
,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
25 citations
,
March 2012 in “Journal of Dermatological Science” Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
August 2023 in “Natural Resources for Human Health” Vegetarians should take B vitamin supplements to avoid health issues.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.
15 citations
,
February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
7 citations
,
October 2019 in “Clinical, Cosmetic and Investigational Dermatology” Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.
179 citations
,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
61 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Beta-catenin is crucial for skin cell growth, development, and cancer formation.
37 citations
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March 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
34 citations
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April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
24 citations
,
September 2005 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
18 citations
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April 2019 in “Archives of Dermatological Research” Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
86 citations
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August 2011 in “Toxicological sciences” TCDD speeds up skin barrier formation by increasing certain gene expressions.
19 citations
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August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
February 2024 in “PloS one” Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
May 2022 in “Frontiers in Cell and Developmental Biology” miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
6 citations
,
November 2010 in “Histochemistry and cell biology” The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
December 2025 in “Journal of Cell Communication and Signaling” Vitamin D receptor is crucial for hair health and may help treat hair loss.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
40 citations
,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
28 citations
,
January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
11 citations
,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.