research Brief Report: Requirement of TACE/ADAM17 for Hair Follicle Bulge Niche Establishment
TACE/ADAM17 is essential for maintaining healthy hair and hair follicle stem cells.
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research Transarterial chemoembolization (TACE) combined with donafenib as first-line therapy for unresectable hepatocellular carcinoma (uHCC): A real-world clinical study.
The combination of TACE and Donafenib is effective and tolerable for treating unresectable liver cancer.
research LPA-producing enzyme PA-PLA1α regulates hair follicle development by modulating EGFR signalling
The enzyme PA-PLA1α is important for proper hair follicle development.
research Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.
Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
research iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice
A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Anti-androgenic activities of Ganoderma lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Congenital hair loss disorders: Rare, but not too rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
research Freeze-Drying of Platelet-Rich Plasma: The Quest for Standardization
The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
research The role of lysophosphatidic acid in the physiology and pathology of the skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes
UV-B light increases inflammation-related substances in acne-related skin cells.
research Cosmetic potential of Southeast Asian herbs: an overview
Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.
research Sorafenib combined with hepatectomy in patients with intermediate-stage and advanced hepatocellular carcinoma
Sorafenib after liver surgery may increase survival for some liver cancer patients.
research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research Pantothenic acid promotes dermal papilla cell proliferation in hair follicles of American minks via inhibitor of DNA Binding 3/Notch signaling pathway
Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
research The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research Application and Progress of Cultured Models of Gallbladder Carcinoma
Advancements in cultured models improve understanding and treatment of gallbladder cancer.
research GREASY SCALING PITYRIASIS AMIANTACEA AND ALOPECIA: A SYNDROME IN SEARCH OF A CAUSE
The cause of the syndrome with scalp scaling and hair loss is unknown.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Effect of Vitamin D on the Expression of Inflammatory Biomarkers in Cultured Sebocytes Treated withPropionibacterium acnesor Ultraviolet B Irradiation
Vitamin D may help reduce inflammation in acne.
research Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice
Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
research A STUDY OF CLINICAL PARAMETERS IN THE DIAGNOSIS OF POLYCYSTIC OVARIAN SYNDROME
Evaluating various physical and health factors helps diagnose polycystic ovarian syndrome (PCOS).
research A Review of U.S. Patents in the Field of Organic Process Development Published during July and August 2004
The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
research REV7: a small but mighty regulator of genome maintenance and cancer development
REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.