Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
STAT5 and Sox18 are crucial for hair growth and wound healing.
Hedgehog signaling can create new hair follicles in adult skin but may increase cancer risk.
Hedgehog signaling can create new hair follicles but may also cause tumors.
January 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” AP-2α and AP-2β are crucial for healthy skin and hair.
June 2025 in “Cell Regeneration” Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.
127 citations
,
January 2008 in “PloS one” Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
44 citations
,
July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
22 citations
,
April 2023 in “The Journal of Cell Biology” Calcium signaling in skin cells is crucial for communication and regeneration.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
34 citations
,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
5 citations
,
February 2025 in “Cell Reports” Skin acetyl-CoA synthesis is crucial for overall lipid balance.
86 citations
,
November 2020 in “Annals of Oncology” Early intervention and tailored management can reduce skin side effects from cancer treatments.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
11 citations
,
July 2024 in “Cancers” Preventing and managing skin issues from cancer treatment is crucial, especially in high UV areas like Australia and New Zealand.
10 citations
,
June 2021 in “EMBO reports” When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.
2 citations
,
May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
February 2026 in “International Journal of Molecular Sciences” Removing Lrig1-positive cells in mice leads to temporary loss of sebaceous glands.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
June 2025 in “Cancer Management and Research” Improving hair health and managing conditions can enhance scalp cooling effectiveness in preventing hair loss during chemotherapy.
24 citations
,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
18 citations
,
March 2016 in “Journal of Investigative Dermatology” Vitamin D and calcium are essential for normal hair growth.
13 citations
,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
7 citations
,
November 2021 in “Anais Brasileiros de Dermatologia” Skin side effects from cancer treatments can lead to changes in therapy and are common, with nail changes being the most frequent.
2 citations
,
May 2024 in “International Journal of Molecular Sciences” Targeting CD169+ skin macrophages may help treat psoriasis.