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research Analysis of the human diseasome using phenotype similarity between common, genetic and infectious diseases

85 citations , June 2015 in “Scientific Reports”

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

research Significance of the polyglutamine tract polymorphism in the androgen receptor

54 citations , November 2001 in “Urology”

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

research Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers

52 citations , January 2020 in “Scientific Reports”

NLCs with manual massage greatly improve clobetasol delivery to hair follicles.

research An Analysis of Follicular Punches, Mechanics, and Dynamics in Follicular Unit Extraction

45 citations , August 2013 in “Facial Plastic Surgery Clinics of North America”

Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.

research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome

40 citations , March 2016 in “The Journal of Clinical Endocrinology & Metabolism”

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function

31 citations , July 2004 in “Molecular Medicine”

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Psoriasis Patients Demonstrate HLA-Cw*06:02 Allele Dosage-Dependent T Cell Proliferation When Treated With Hair Follicle-Derived Keratin 17 Protein

research Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein

27 citations , April 2018 in “Scientific Reports”

Psoriasis patients' immune response to a hair protein depends on their specific gene type.

Hormonal Parameters in Androgenetic Hair Loss in Males

research Hormonal Parameters in Androgenetic Hair Loss in the Male

21 citations , October 2009 in “Dermatology”

Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.

research What is the Rationale for Androgen Therapy for Women?

20 citations , January 2003 in “Treatments in Endocrinology”

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites

18 citations , March 2020 in “Frontiers in Neuroendocrinology”

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

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