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Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.

Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Elf5 controls skin cell growth and development, making it a potential target for skin treatments.

Blimp1 is crucial for hair follicle growth and skin health.

CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

High ODC and low K1 and K10 may indicate early skin tumors in mice.

Human skin cells can respond to thyroid-stimulating hormone, affecting hair and skin health.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.

A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.

Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.

The new model helps understand and develop treatments for genetic skin disorders like AEC.

Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.

Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.

A girl with Becker naevus syndrome has a genetic variant in the ACTB gene related to her symptoms.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.