research Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
Meis2 is essential for touch sensation and nerve function in mice.
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research Author Response: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
research Faculty Opinions recommendation of Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions.
The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Epithelial skirt and bulge of human facial vellus hair follicles and and associated Merkel cell-nerve complex
Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
research Receptor types in cat hairy skin supplied by myelinated fibers.
Cats' hairy skin has different touch receptors connected by myelinated fibers.
research Merkel cell differentiation in trichoblastoma
Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.
research Rippled‐pattern trichomatricoma
A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
research Linkage of Monilethrix to the Trichocyte and Epithelial Keratin Gene Cluster on 12q11-q13
research Multifunctional Merkel cells: Their roles in electromagnetic reception, finger-print formation, Reiki, epigenetic inheritance and hair form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn
Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
research Early inductive events in ectodermal appendage morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
research A pure, monolayer culture of Merkel cells from sinus hair follicles of the rat
Adding fetal calf serum helps Merkel cells survive and change shape.
research Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Activin A and follistatin control when ear hair cells form in mice.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research The Hair Cell Analysis Toolbox: A machine learning-based whole cochlea analysis pipeline
The Hair Cell Analysis Toolbox automates and improves the analysis of cochlear hair cells using machine learning.
research Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins
Reptile skin hardens by layering beta-proteins on keratin.
research Metallothionein expression during wool follicle development in foetal sheep
Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
research Telocytes of the male reproductive system: dynamic tissue organizers
Telocytes help organize male reproductive tissues and their changes can lead to diseases.
research Three-dimensional architecture and linearized mapping of vibrissa follicle afferents
Large-scale reconstructions enhance understanding of vibrissal sensory mapping in the brain.
research The Story of the Finest Armor: Developmental Aspects of Reptile Skin
Reptile skin protects and prevents water loss, helping them adapt to land.
research Multifocal Malignant Proliferating Trichilemmal Tumour: A Diagnostic Imitator Beyond the Scalp
Recognizing specific markers is crucial for correctly diagnosing and treating rare multifocal MPTT in males.
research Microtubule associated protein (MAP‐2) expression defines the companion layer of the anagen hair follicle and an analogous zone in the nail unit
MAP-2 is crucial for the structure of hair follicles and nails.
research Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium
Pax9 is crucial for proper tongue surface development and preventing skin-like changes.
research Basement Membranes in Experimentally Induced Skin Tumors
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Reviewer #1 (Public review): Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
research EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals
EGFR signaling is essential for ear cell regeneration in both birds and mammals.