4 citations
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June 2020 in “British Journal of Pharmacology” Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
4 citations
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May 2019 in “PubMed” Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.
7 citations
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March 2012 in “Journal of Investigative Dermatology” Some thymic peptides can increase human hair growth, while others may inhibit it.
1 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” New molecules can prevent cell death in hair follicles.
2 citations
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
9 citations
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February 2022 in “Biomedicines” Testosterone treatment may change estrogen receptor methylation in AFAB individuals.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
29 citations
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December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
85 citations
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January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
January 2018 in “Bradford Scholars (University of Bradford)” SWI/SNF complexes are crucial for wound healing but not for hair growth.
44 citations
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March 2012 in “Molecular Carcinogenesis” Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.
42 citations
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December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
12 citations
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September 2021 in “PLoS ONE” WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.
14 citations
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January 2017 in “Pharmacological Reports” TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
54 citations
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October 2023 in “Oncogene” p63 is essential for controlling epithelial stem cells and tissue health.
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
18 citations
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June 2011 in “Cell stem cell” MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
11 citations
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November 2023 in “Journal of Advanced Research” Activating ALDH2 can boost hair growth.
5 citations
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December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
April 2018 in “Journal of Investigative Dermatology” Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
47 citations
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June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
16 citations
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August 2022 in “Nature Communications” ROR2 is essential for hair follicle stem cell renewal and maintenance.
September 2017 in “Journal of Investigative Dermatology” Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
41 citations
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December 1988 in “Journal of Investigative Dermatology”
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.